ROCKY MOUNTAIN SECTION OPTICAL SOCIETY OF AMERICA & IEEE LASERS AND ELECTROOPTICS SOCIETY March Meeting Date: Thursday, 19 Mar. 1998 Time: 7:00 PM refreshments, 7:30 PM talk Place: National Institute of Standards and Technology 325 Broadway, Boulder, CO Room 1107 Optical Biopsy: Optical Technologies for Minimally-Invasive Diagnosis of Cancer Irving J. Bigio, Ph.D. Bioscience & Biotechnology Group MS-E535 Los Alamos National Laboratory Los Alamos, NM 87545 505-667-7748 fax: 505-665-4637 Abstract: A variety of optical spectroscopic techniques are being investigated for the development of noninvasive diagnosis of various cancers. These have the potential to reduce the need for surgical biopsies while providing improved diagnostic reliability. Biography: Irving J. Bigio received his Ph.D. in Physics from The University of Michigan in 1974 and since then has conducted research in laser physics and optics at Los Alamos National Laboratory, including service as the Group Leader for the Laser Science and Applications Group (1988-1994). In 1976-77 Dr. Bigio received a Fulbright Award and spent a year as a visiting professor at the Weizmann Institute of Science, in Israel. He has also spent summer leave periods at the University of Copenhagen, Denmark, and during 1994-95 he spent a sabbatical leave as a Guest Fellow at the University of Oxford, England. In recent years he has focused his research on biomedical applications of lasers and optics, including molecular dynamics of DNA and proteins, and minimally-invasive medical diagnostics and therapeutics. He holds several patents for biomedical optics instrumentation, and he has received three R&D-100 Awards for the development of optical devices for biomolecular spectroscopy and medical applications. Dr. Bigio is a Fellow of the OSA.